The first polls are set to open in Vermont at 5am (10:00 GMT).
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The first results are expected on Tuesday as polls begin to close at 23:00 GMT. But final results might take days.
As Israel grapples with an inconclusive election, Palestinians face West Bank closures and Gaza killings.
Americans deliver their verdict on Donald Trump's tumultuous second presidency Tuesday in midterm elections that threaten to shatter his grip on Washington, with Democrats poised to seize the House and challenge for control of the Senate.
